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Lactic acidosis


Definition:

Lactic acidosis is when lactic acid builds up in the bloodstream faster than it can be removed. Lactic acid is produced when oxygen levels in the body drop.

Causes:

The most common cause of lactic acidosis is intense exercise. However, it can also be caused by certain diseases, such as:

A common medicine used to treat diabetes called metformin can also cause lactic acidosis. If you take this medicine, have your electrolyte levels checked 1 to 2 weeks after starting it.

Symptoms:

Symptoms may include:

  • Nausea
  • Weakness
Exams and Tests:

Tests may include a blood test to check electrolyte levels

Treatment:

The main treatment for lactic acidosis is to correct the medical problem that causes the condition.

References:

Seifter JL. Acid-base disorders. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine. 24th ed. Philadelphia, PA: Elsevier Saunders; 2011:chap120.

Strayer RJ. Acid-base disorders. In: Marx JA, Hockberger RS, Walls RM, eds. Rosen's Emergency Medicine. 8th ed. Philadelphia, PA: Elsevier Saunders; 2014:chap 99.


Review Date: 11/2/2014
Reviewed By: Linda J. Vorvick, MD, Medical Director and Director of Didactic Curriculum, MEDEX Northwest Division of Physician Assistant Studies, Department of Family Medicine, UW Medicine, School of Medicine, University of Washington, Seattle, WA. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team.

The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed physician should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. Copyright 2002 A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.

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