Penn Breakthroughs

Shedding Light on Melanoma

Abramson Cancer Center's nationally-recognized pigmented lesion/melanoma group leads the way in prevention, diagnosis and treatment of melanoma.

By 2010, it is estimated that 1 in 50 Americans will develop melanoma, a potentially lethal skin cancer — a startling statistic that Penn has every intention of delaying. And it all starts with the Abramson Cancer Center of the University of Pennsylvania's nationally-recognized Pigmented Lesion/Melanoma Group.

For more than thirty years, we have been regarded as the experts in clinical care, melanoma research and treatment. In fact, our doctors at Penn were the first to identify the progressive stages from a mole to early melanoma, a medical breakthrough that makes it possible for doctors everywhere to intercept the disease at a curable stage.

“Penn's breakthrough research in identifying genetic abnormalities allows us to develop targeted therapies, thus revolutionizing our ability to treat melanoma,” said Lynn Schuchter, MD, Professor of Medicine (Hematology/Oncology) and leader of the Melanoma Program.

Prevention / Prognosis
Here at Penn, information gathered through melanoma research has increased the understanding of this disease including:

  • Identifying melanoma staging systems and their ability to predict the outcome
  • Whether the number of advanced melanomas can be decreased through sun protection measures and self-examination for early detection
  • How to predict whether melanoma has spread to the lymph nodes

The Key to Early Detection of Skin Cancer is Awareness

To detect the disease early, follow the ABCDE screening process to be aware of suspicious moles:

  • Asymmetry – Do both halves match?
  • Border – Is it uneven or irregular?
  • Color – Different shades of tan, brown, black and pink
  • Diameter – Larger than a pencil eraser
  • Evolution – Any change in size, shape, color or elevation of a mole or skin lesion

Treatment
Beyond expert diagnosis, the team is also a nationally recognized interdisciplinary group of doctors who have worked together for years in caring for melanoma patients. Because we are committed to developing more effective treatments, the comprehensive program also features dedicated research with clinical trials. This includes a therapy that blocks several enzymes that are overactive in melanoma, significantly enhancing the effectiveness of chemotherapy.

Melanoma is treatable. Through early detection and treatment, it can be one of the most curable types of skin cancer, which is why where you turn first matters most.

 


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