The Center for Bloodless Medicine & Surgery at Pennsylvania Hospital
 

Fall 2004

Surgery Success Story
Bloodless Total Hip Replacement
Alternatives to Blood Transfusions
Physician Profile
 

Bloodless Total Hip Replacement Surgery

Fall 2004

Severe blood loss can be an issue with any major surgery, including total hip replacement surgery. An average of one to two pints of blood can be lost during this surgery. However, bloodless surgery, or surgery performed without the use of whole blood or blood products, may be an option for patients who object to blood transfusions for religious or personal reasons.

Key to the success of bloodless hip replacement surgery is the use of state-of-the-art equipment, as well as the implementation of procedures to minimize blood loss. Prior to the surgery, the patient’s medications can be adjusted and the patient can also receive a supply of vitamins and iron to increase their ability to make more hemoglobin. During the operation, the surgeon works with the anesthesiologist to achieve minimal blood loss. The anesthesiologist uses surgical monitoring to determine the amount of blood lost and to prevent fluctuations in blood pressure. By using hypotensive anesthesia, a constant low blood pressure can be maintained, decreasing total blood loss.

Another new advancement in bloodless hip replacement surgery is the use of a genetically engineered growth factor called epoetin alfa, more commonly known as PROCRIT®. This substance is naturally produced by the kidneys to increase red blood cells, so that more oxygen can be carried to the tissues. In addition to other uses, PROCRIT® is administered to surgical patients, prior to surgery, to reduce the need for a blood transfusion during surgery.

Acute normovolemic hemodilution (ANH) is a method also used prior to surgery, which allows a patient to use his or her own blood just before surgery. The patient’s blood is diluted with a volume expander, such as crystalloids or colloids, which are solutions used to increase the volume of fluid in the circulating blood. By doing this, if a patient loses fluid during surgery, the solution would be lost rather than the red blood cells. During this process, the blood is kept in a continuous loop, or closed circuit.

By using ANH, surgery can take place without using blood from an outside source. A decision to have total hip replacement surgery without the use of blood or blood products is a matter of personal choice, and should be discussed with a primary care physician and an orthopaedic surgeon.

 


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