Cancer care

At Penn Medicine, pioneering research, clinical expertise, and compassionate care join forces to transform cancer treatment in the region and worldwide, delivering personalized care that advances science, inspires hope, and saves lives.
Cancer survivor embraces loved one at Abramson Cancer Center

Opening new doors to the most advanced cancer care

At Penn Medicine, we are dedicated to delivering innovative and compassionate cancer care. Our cancer centers bring together a committed team of specialists, including oncologists, surgeons, and researchers, to provide the latest advancements in cancer prevention, diagnostics, and treatment. Our faculty is devoted to ensuring that every one of our 300,000+ patients receive the highest standards of care.

Penn Medicine’s Cancer System is led by the Abramson Cancer Center with locations at the Hospital of the University of Pennsylvania, Pennsylvania Hospital, Penn Presbyterian Medical Center, Chester County Hospital, and outpatient locations in the Philadelphia and NJ suburbs. Beyond the greater Philadelphia region, the system includes programs at the Ann B. Barshinger Cancer Institute at Lancaster General Health, Doylestown Health, and Princeton Medical Center.

Within the Penn Medicine cancer community, patients will find:

  • A specialized multidisciplinary team focused on each patient’s unique disease 
  • State-of-the-art facilities 
  • The latest in cancer prevention methods 
  • Disease-specific radiologists and pathologists ensuring the most accurate diagnosis leading to precision treatment plans 
  • Lifelong follow-up care 
  • Access to life-changing clinical trials
  • Leading ground-breaking basic science research
National Cancer Institute Designated Comprehensive Cancer Center badge on top of shot of hospital

Rated “exceptional” by The National Cancer Institute

Penn Medicine’s Abramson Cancer Center is a world leader in cancer research, patient care, and education. Our status as a national leader in cancer care is reflected in our continuous designation as a Comprehensive Cancer Center by the National Cancer Institute (NCI) since 1973, one of 7 such centers in the United States. The ACC is also a member of the National Comprehensive Cancer Network, one of a select few cancer centers in the U.S., that are working to promote equitable access to high-quality, advanced cancer care.

Penn Medicine proton therapy researchers in lab

What’s next is happening right now

Cancer research is advancing rapidly thanks to innovative approaches uncovered through Penn Medicine’s translational research and clinical trials. Our goal is to bring these emerging therapies from the research bench directly to the patient’s bedside.

Richard Edmund Phillips, MD, PhD, at microcope in brain cancer research lab

Specialties

Innovation lives here: Shaping the future of cancer treatment

As an academic medical center, Penn Medicine is leading the way in cancer treatment, offering our patients access to advanced therapies. Breakthrough treatments like CAR T cell therapy, which uses the patient’s immune system to target cancer cells, and TumorGlow® which aids surgeons in effectively identifying and removing cancerous tissues, were discovered by Penn Medicine researchers. Penn Medicine is home to the Basser Center for BRCA, the first comprehensive center for research, treatment and prevention of BRCA-related cancers.

Beyond developing new treatment options, our researchers are looking at ways to “intercept” hereditary cancer before it even develops. By studying the changes in cells as they become cancerous, the goal is to catch these changes from the very beginning to halt or reverse the process, effectively preventing cancer from developing.

We also offer the region’s only academic medical center dedicated to proton therapy, a non–invasive, incredibly precise cancer treatment that uses a beam of protons moving at very high speeds to destroy cancer cells. Our commitment to offering groundbreaking treatments puts Penn Medicine in the position to continually improve outcomes and enhance our patients’ day-to-day lives.

Cancers we treat

Seamless care at our expert cancer centers

Dedicated to providing both leading-edge and compassionate cancer care, the Abramson Cancer Center and Ann B. Barshinger Cancer Institute at Penn Medicine deliver extensive diagnostics, treatments, and support. With locations throughout the southeastern Pennsylvania and New Jersey regions, you can access the most advanced cancer care close to home.

Partners in your care every step of the way

Penn Medicine cancer specialists ensure all patients receive care that addresses all their needs. From diagnosis through recovery, we provide leading services and support to optimize your health and well-being.
Friendly nurse helps patient during an outdoor health fair or free clinic event

Community outreach and engagement

Working together with community members, health care providers, and local leaders deepens our understanding of cancer risk factors and disparities. This insight inspires us to jointly develop research, strategies, programs, and policies aimed at increasing access to cancer care—from prevention and screening to treatment and survivorship. Our goal is to reduce the burden of cancer and improve health outcomes for all.

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Patient stories

From survivor to inspiring others to exercise

From survivor to inspiring others to exercise

Doris Piccinin uses her own firsthand experience as a breast cancer survivors to help other survivors. “I’m excited to see a lightbulb go on for people when they realize that not all physical activity is the same, and to see them recognize and understand the questions to ask when they’re having limitations. That’s where I gain my inspiration.”

An unexpected ovarian cancer diagnosis

An unexpected ovarian cancer diagnosis

“I’m thankful for the support and many prayers from my family and friends. I appreciate that I received care close to home and grateful that Dr. Soriano found my cancer,” said Donna Frandsen.

Genetic knowledge helps catch cancer early

Genetic knowledge helps catch cancer early

“I didn’t know about BRCA at all before my sister’s diagnosis—it was a total learning curve,” Trudy Orthey said. “If you know that your family carries this gene mutation, don’t be afraid to talk about it. I did and it saved my life. It also has a ripple effect to your family and future generations.”

A five-time survivor who keeps fighting follicular lymphoma

A five-time survivor who keeps fighting follicular lymphoma

“I have been truly thankful for the medical expertise and personal care I have and continue to receive at Penn Medicine while managing this cancer that continues throughout my life,” said Sharon Dunkel.

A mom-inspired clinical trial journey to help others

A mom-inspired clinical trial journey to help others

“I wanted to participate in a clinical trial because I was inspired by my mom,” Kate Korson said. “I saw how brave she was and the success she had on a clinical trial. I felt like I received the best possible care by taking part in a clinical trial, and it feels good to know that I’m helping others by contributing to cancer research.”

Coming home to ‘Team Penn’: Kate’s Story

Coming home to ‘Team Penn’: Kate’s Story

From the moment Kate Korson showed up at her first appointment wearing a Penn sweatshirt to symbolize she was on “Team Penn,” every one of her caregivers let her know they were on “Team Kate.” “Penn has now saved all three members of my family,” she said, after participating in a clinical trial.

A senior survivor of uterine cancer at 87

A senior survivor of uterine cancer at 87

"I felt I was in exceptional hands,” said Mimi Reed. Diagnosed with uterine cancer at 86, Reed found care personalized to her goal of maintaining her independence through specialized geriatric oncology care at Penn Medicine Princeton Medical Center.

Creating beauty out of a breast cancer journey

Creating beauty out of a breast cancer journey

“Cancer isn’t just physically grueling. It mentally and emotionally tears you down,” Ginger Mimmo Rohlfing said of her experience navigating HER2-positive breast cancer, chemotherapy, mastectomy, and breast reconstruction surgery. Her paintings of leaf and petal patterns “were a metaphor for putting pieces of myself back together.”

First-ever CAR T cell patient who lived beyond hope

First-ever CAR T cell patient who lived beyond hope

“I’m looking for [extending life by] a day, a week, or a month, and here they are telling me I don't have cancer,” said Bill Ludwig, years later. “It was just like someone told you, ‘You won the lottery.’”

A diagnosis that ripples through the family

A diagnosis that ripples through the family

“It’s harder to find out your sister has cancer and a BRCA mutation than to find out for yourself,” said Laura Temple. Testing and treatment have made all the difference for the three BRCA-positive sisters who are now breast cancer survivors. They are grateful for Susan Domchek, MD, answering questions about research that could benefit their children.

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